Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Diabetes genomics research has illuminated single nucleotide polymorphism (SNP) in several genes including, fat mass and obesity associated (FTO) (rs9939609 and rs9926289), potassium voltage-gated channel subfamily J member 11 (rs5219), SLC30A 8 (rs13266634) and peroxisome proliferator-activated receptor gamma 2 (rs1805192). 31823921

2019

dbSNP: rs3856806
rs3856806
0.080 GeneticVariation BEFREE The TT genotype of rs3856806 in PPAR<i>γ</i> had an increased risk for diabetes. 29849618

2018

dbSNP: rs2920502
rs2920502
0.010 GeneticVariation BEFREE The GG genotype of rs2920502 in PPAR<i>γ</i> had a decreased risk for diabetes. 29849618

2018

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Genotyping for Pro12Ala and Trp64Arg polymorphism in postmenopausal women may have the clinical benefit of predicting hyperglycaemia, thereby contributing to the prevention of diabetes mellitus development in the future. 29464546

2018

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Genotyping for Pro12Ala and Trp64Arg polymorphism in postmenopausal women may have the clinical benefit of predicting hyperglycaemia, thereby contributing to the prevention of diabetes mellitus development in the future. 29464546

2018

dbSNP: rs1440763451
rs1440763451
0.010 GeneticVariation BEFREE The gain-of-function Q84R polymorphism in TRIB3 is associated with increased risk of diabetes and atherosclerosis. 26855171

2016

dbSNP: rs3856806
rs3856806
0.080 GeneticVariation BEFREE The C1431T polymorphism of peroxisome proliferator activated receptor-γ (PPAR-γ) gene is related to diabetes and metabolic-syndrome. 25896411

2015

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa. 24447396

2014

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Proliferator-activated receptor gamma Pro12Ala interacts with the insulin receptor substrate 1 Gly972Arg and increase the risk of insulin resistance and diabetes in the mixed ancestry population from South Africa. 24447396

2014

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Diabetes risk alleles in PPAR-γ2 (rs1801282) and PTPRD (rs17584499) are associated with pioglitazone therapeutic efficacy. 23147557

2013

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population. 23006958

2012

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population. 23006958

2012

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controversial. 22017455

2012

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE The interaction of the PPARγ Pro12Ala polymorphism with diabetes and cardiovascular risk is controversial. 22017455

2012

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE There was no convincing association between any polymorphism of PPARα and PPARγ and each individual component of the metabolic syndrome, except for the relationship of the P12A polymorphism with diabetes. 21877956

2012

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE There was no convincing association between any polymorphism of PPARα and PPARγ and each individual component of the metabolic syndrome, except for the relationship of the P12A polymorphism with diabetes. 21877956

2012

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Our findings shows the association of these two polymorphisms with serum triglyceride levels, which was increased in the order of P12P-CC < P12P-CT < P12A-CC < P12A-CT in the CHD patients with diabetes. 21833536

2011

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Our findings shows the association of these two polymorphisms with serum triglyceride levels, which was increased in the order of P12P-CC < P12P-CT < P12A-CC < P12A-CT in the CHD patients with diabetes. 21833536

2011

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial. 21795447

2011

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial. 21795447

2011

dbSNP: rs3856806
rs3856806
0.080 GeneticVariation BEFREE Another PPARγ polymorphism, the C1431T, is in strong linkage disequilibrium with Pro12Ala and has been shown to be associated with body weight, but its association with diabetes is controversial. 21795447

2011

dbSNP: rs3856806
rs3856806
0.080 GeneticVariation BEFREE The C1431T polymorphism in peroxisome proliferator-activated receptor-γ (PPARγ) has been shown to be associated with diabetes, obesity, and metabolic syndrome. 21643757

2012

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE The authors highlight these challenges and biases using an illustrative example: meta-analysis of interactions between the Pro12Ala variant of the peroxisome proliferator-activated receptor gamma (PPARgamma) gene and various diet and lifestyle factors in the risk of diabetes. 20406760

2010

dbSNP: rs1805192
rs1805192
0.100 GeneticVariation BEFREE The authors highlight these challenges and biases using an illustrative example: meta-analysis of interactions between the Pro12Ala variant of the peroxisome proliferator-activated receptor gamma (PPARgamma) gene and various diet and lifestyle factors in the risk of diabetes. 20406760

2010

dbSNP: rs1801282
rs1801282
0.100 GeneticVariation BEFREE Studies on the association of the Pro12Ala and C1431T polymorphisms of PPAR? with diabetes and obesity have revealed extensive population-dependent variations. 19805902

2009